FACT BRIEF

Are side effects of the COVID-19 vaccines worse than those from flu shots?

Saturday, April 3, 2021

By Lisa Freedland

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YES

The three COVID-19 vaccines available in the U.S. appear to produce a significantly higher incidence of side effects than ordinary flu shots, which scientists say is one indication of their greater effectiveness.

An Emory University researcher reported on Feb. 24 that, based on data submitted to the Food and Drug Administration by the manufacturers, the difference is most pronounced after the second dose for people under 60 years of age. Side effects, notably pain, fatigue and headaches, were more prevalent with the Moderna vaccine, followed by the Pfizer shot and then the single-dose Johnson & Johnson shot.

The strength of the side effects is an indication that the body is creating more antibodies, leading to stronger defenses against the disease. Some health experts believe learnings from the COVID-19 vaccines will be used to improve existing vaccines against other diseases.

This fact brief is responsive to conversations such as this one.

Sources

Jesse O’Shea MD Chart posted on Twitter: Comparing side effects from COVID-19 vaccines and a flu vaccine

Jesse O'Shea MD Tweet: Side effects data drawn from submissions to FDA

Jesse O’Shea MD Biography

Healthline COVID-19 vaccine may be more effective than the flu shot

Centers for Disease Control Possible side effects after getting a COVID-19 vaccine

New York Times The most common questions about vaccination side effects, answered

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